A New Variant of Glucose - 6 - Phosphate D ehydrogenase Deficiency
نویسنده
چکیده
A variant of glucose-6-phosphate-dehyelectrophoretic mobility (B), and utilizadrogenase deficiency associated with tion of substrate analogues 2-deoxy-G6P chronic hereditary hemolytic anemia was and deamino-NADP were normal. The discovered in a 9-yr-old white male. The activity of G6PD in the leukocytes and erythrocytes contained 5% of normal platelets was 15% and 28% of normal enzyme activity, the Km NADP was two values, respectively, but bactericidal acto three times normal, the pH optimum tivity and platelet function were unwas decreased, and the heat stability affected by the deficiency of G6PD. was markedly decreased. The Km G6PD,
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تاریخ انتشار 2005